What is ALC ?
Acetyl-L-Carnitine, ALCAR or ALC, is an acetylated form of L-carnitine. It is naturally produced by the body, although it is often taken as a dietary supplement. Acetylcarnitine is broken down in the blood by plasma esterases to carnitine which is used by the body to transport fatty acids into the mitochondria for breakdown.
Acetyl-L-carnitine is used for a variety of mental disorders including Alzheimer's disease, age-related memory loss, late-life depression, thinking problems related to alcoholism, and thinking problems related to Lyme disease. It is also used for Down syndrome, poor circulation in the brain, cataracts, nerve pain due to diabetes, nerve pain due to drugs used in the treatment of AIDS, and facial paralysis.The body can convert L-carnitine to acetyl-L-carnitine and vice versa
What is effective dosage of ALC supplementation
1) For Alzheimer’s disease: 1500-4000 mg daily, usually divided into two or three doses during the day.
2) For In age-related memory loss: 1500-2000 mg daily.
3) For depression in the elderly: 1500-3000 mg daily in divided doses.
4) For male infertility:
4.1 gram of acetyl-L-carnitine plus 2 grams of L-carnitine daily.
4.2 1 gram of acetyl-L-carnitine plus 2 grams of L-carnitine daily.
5) 3000 mg daily has been used to fasten fat loss.
What are the benefits of ALC supplementation?
Improving memory problems in elderly people.
Improving memory in people who use alcohol excessively. Taking acetyl-L-carnitine seems to improve memory in 30-60 year-old people whose use of alcohol has produced long-term thinking problems.
Reducing nerve pain (neuropathy) caused by diabetes. Acetyl-L-carnitine reduces pain best in people who have not had diabetes for a long time or who have poorly controlled type 2 diabetes.
Treating Peyronie’s disease, a connective tissue disease in men. Acetyl-L-carnitine seems to be more effective than a drug called tamoxifen for reducing pain and slowing worsening of the condition.
Treating male infertility caused by inflammation of some reproductive organs and tissues (prostate, seminal vesicles, and epididymis). Taking acetyl-L-carnitine by mouth, along with L-carnitine for 6 months, seems to increase sperm count and sperm movement. The carnitines are used following 2 months of treatment with non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin.
What are the side effects of ALC supplementation?
Acetyl-L-carnitine is safe for most adults. It rarely causes some side effects including stomach upset, nausea, vomiting, and restlessness. It can cause a "fishy" odor of the urine, breath, and sweat.