Mayur Deshpande
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Nutritional Supplements Library Chondroitin sulphate

Nutritional Supplements Library

Chondroitin sulphate


What is Chondroitin sulphate?

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Chondroitin is a molecule that occurs naturally in the body. It is a major component of cartilage -- the tough, connective tissue that cushions the joints. Chondroitin is commonly sold as chondroitin sulfate, in capsules or tablets. It is often combined with glucosamine and sometimes manganese as well. Manganese is a trace element necessary for normal bone health. Chondroitin sulfate is one of the major constituents of cartilage. Chondroitin sulfate consists of repeating chains of molecules called mucopolysaccharides. It is a primary part of cartilage. Classified as a type of glycosaminoglycan, chondroitin sulfate is rich in sulfur and is a relative of glucosamine. Animal cartilage is the only significant food source of Chondroitin sulfate.


What is the effective dosage of Chondroitin Sulfate supplementation?

Chondroitin is commonly sold as chondroitin sulfate, in capsules or tablets. It is often combined with glucosamine and sometimes manganese as well. Manganese is a trace element necessary for normal bone health. The total amount of manganese from foods and supplements should not exceed 11 mg per day, but several combination supplements for arthritis (containing glucosamine, chondroitin, and manganese) have more than that. Read labels carefully, and consider choosing a supplement without manganese.
Pediatric - Chondroitin is not recommended for children. It is mainly used for treatment of osteoarthritis (a condition that affects adults), and its safety for children has not been studied.
Adult - 400 mg three times a day or 600 mg two times a day, taken by mouth.


What are the benefits of Chondroitin Sulfate supplement?

Osteoarthritis -Not only does chondroitin sulfate provide structure and holds water and nutrients, but it allows other molecules to move through cartilage. This is a very important property, as there is no blood supply to cartilage. As a result, joint support is greatly increased through supplementation.Chondroitin sulfate and similar compounds are also exist in the bladder and lining of blood vessels. Here they help to prevent abnormal movement of blood, urine, or components across the barrier of the vessel or bladder wall.
Japanese researchers have found that chondroitin sulfate may play a role in determining the viscosity and elasticity of tissues and fluids. A recent in vitro study done by scientists in Belgium found that chondroitin sulfate had potentially beneficial effects on human cartilage cells.
Bladder Conditions - One study found that intravesicular chondroitin sulfate (irrigating the bladder with chondroitin sulfate) may help relieve symptoms of interstitial cystitis. Another single study found that chondroitin sulfate, taken orally, might help reduce symptoms of overactive bladder.
Other - Other conditions for which chondroitin sulfate has been suggested include preterm labor, Alzheimer's disease, heart disease, and osteoporosis. However, no studies have yet evaluated these claims.


What are the side effects of Chondroitin Sulfate supplement?

Chondroitin sulfate is safe and relatively free of side effects when used at the recommended daily dosage, at least for short periods of time. Some people may experience mild stomach upset. So far, few studies have investigated the safety and effectiveness of chondroitin sulfate when used for long periods of time.
Note - In the past, researchers have found that some chondroitin sulfate supplements did not contain the amount of chondroitin sulfate stated on the label. The same was true of some combination glucosamine and chondroitin sulfate supplements. Ask your doctor to recommend a brand, or choose a brand you trust.Many chondroitin sulfate supplements are made from cow cartilage. If you are a vegetarian, look for a supplement made from algae instead.