Nutritional Supplements Library
What is Vinpocetine ?
Vinpocetine (pronounced vin-poe-ce-teen) is a synthetic compound derived from vincamine, a substance found naturally in the leaves of the lesser periwinkle plant . Vinpocetine was developed in the late 1960s.Vinpocetine is available as a prescription drug in Europe and Japan. In the the United States and Canada, it's sold in health food stores and online as a dietary supplement. Vinpocetine is widely marketed as a supplement for vasodilation and as a nootropic for the improvement of memory. In other words, Vinpocetine may help support brain functions such as concentration and memory by activating cerebral metabolism.
What is the effective dosage of Vinpocetine supplementation?
It is recommended that first-time users ingest only 2-5 mg of vinpocetine with meals to make sure they are not hypersensitive to it. Users may then increase the dosage to 10-40 mg a day (which may, although very rarely, cause some light side-effects).
What are the benefits of Vinpocetine supplementation?
• Vinpocetine supports healthy blood circulation and oxygen flow to the brain.Vinpocetine is a powerful antioxidant and it also enhances the delivery of glucose to the brain. Glucose is the brains primary fuel source, and without it the brain will shut-down.Not surprisingly, athletes who supplement with vincamine report significant improvement in visual acuity, memory and focus. Vincamine supports the brain and maintains its function.
• Vincamine is extremely thermogenic. It causes rapid losses in bodyfat, and it accomplishes this by stimulating the release of the hormone norepinephine. It is, not surprisingly, a popular ingredient in over-the-counter weight loss supplements.
• Vinpocetine has been shown to selectively inhibit voltage-sensitive Na+ channels, resulting in a dose-dependent decrease in evoked extracellular Ca+ ions in striatal nerve endings.The Na+ channel inhibiting properties of vinpocetine are thought to contribute to a general neuroprotective effect through blockade of excitotoxicity and attenuation of neuronal damage induced by cerebral ischemia/reperfusion.
What are the side effects of Vinpocetine supplementation?
Side effects of vinpocetine may include indigestion, nausea, dizziness, anxiety, facial flushing, insomnia, headache, drowsiness and dry mouth. Vinpocetine may also cause a temporary drop in blood pressure.In clinical trials adverse effects have been reported infrequently, but the trials were not long-term.
The safety of vinpocetine in pregnant women has not been evaluated.